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Publications

The full list of publications can be found on: PubMed.gov

Colomb, F., & McSorley, H. J. (2025). Protein families secreted by nematodes to modulate host immunity. Current opinion in microbiology, 84, 102582.

Colomb, F., Jamwal, A., Ogunkanbi, A., Frangova, T., Savage, A. R., Kelly, S., Wright, G. J., Higgins, M. K., & McSorley, H. J. (2024). Heparan sulphate binding controls in vivo half-life of the HpARI protein family. eLife, 13, RP99000.

Jamwal, A., Colomb, F., McSorley, H. J., & Higgins, M. K. (2024). Structural basis for IL-33 recognition and its antagonism by the helminth effector protein HpARI2. Nature communications, 15(1), 5226.

Colomb, F., Ogunkanbi, A., Jamwal, A., Dong, B., Maizels, R. M., Finney, C. A. M., Wasmuth, J. D., Higgins, M. K., & McSorley, H. J. (2024). IL-33-binding HpARI family homologues with divergent effects in suppressing or enhancing type 2 immune responses. Infection and Immunity, 92(3), e00395-00323.

Di Carmine, S., Scott, M. M., McLean, M. H., & McSorley, H. J. (2022). The role of interleukin-33 in organ fibrosis. Discovery Immunology, 1(1).

Chauché, C., Rasid, O., Donachie, A. M., Mcmanus, C. M., Löser, S., Campion, T., Richards, J., Smyth, D. J., McSorley, H. J., & Maizels, R. M. (2022). Suppression of airway allergic eosinophilia by Hp-TGM, a helminth mimic of TGF-β. Immunology.

McSorley, H. J., & Smyth, D. J. (2021). IL-33: A central cytokine in helminth infections. Seminars in immunology., 53, 101532.

Meiners, J., Reitz, M., Rüdiger, N., Turner, J.-E., Heepmann, L., Rudolf, L., Hartmann, W., McSorley, H. J., & Breloer, M. (2020). IL-33 facilitates rapid expulsion of the parasitic nematode Strongyloides ratti from the intestine via ILC2- and IL-9-driven mast cell activation. PLOS Pathogens, 16(12), e1009121.

Chauché, C., Vacca, F., Chia, S. L., Richards, J., Gregory, W. F., Ogunkanbi, A., Wear, M., & McSorley, H. J. (2020). A Truncated Form of HpARI Stabilizes IL-33, Amplifying Responses to the Cytokine [Original Research]. Frontiers in Immunology, 11.

Vacca, F., Chauché, C., Jamwal, A., Hinchy, E. C., Heieis, G., Webster, H., Ogunkanbi, A., Sekne, Z., Gregory, W. F., Wear, M., Perona-Wright, G., Higgins, M. K., Nys, J. A., Cohen, E. S., & McSorley, H. J. (2020). A helminth-derived suppressor of ST2 blocks allergic responses. Elife, 9.

Maizels, R. M., Smits, H. H., & McSorley, H. J. (2018). Modulation of Host Immunity by Helminths: The Expanding Repertoire of Parasite Effector Molecules. Immunity, 49(5), 801-818.

Johnston, C. J. C., Smyth, D. J., Kodali, R. B., White, M. P. J., Harcus, Y., Filbey, K. J., Hewitson, J. P., Hinck, C. S., Ivens, A., Kemter, A. M., Kildemoes, A. O., Le Bihan, T., Soares, D. C., Anderton, S. M., Brenn, T., Wigmore, S. J., Woodcock, H. V., Chambers, R. C., Hinck, A. P., . . . Maizels, R. M. (2017). A structurally distinct TGF-β mimic from an intestinal helminth parasite potently induces regulatory T cells. Nature Communications, 8(1).

Osbourn, M., Soares, D. C., Vacca, F., Cohen, E. S., Scott, I. C., Gregory, W. F., Smyth, D. J., Toivakka, M., Kemter, A. M., Le Bihan, T., Wear, M., Hoving, D., Filbey, K. J., Hewitson, J. P., Henderson, H., Gonzàlez-Cìscar, A., Errington, C., Vermeren, S., Astier, A. L., . . . McSorley, H. J. (2017). HpARI Protein Secreted by a Helminth Parasite Suppresses Interleukin-33. Immunity, 47(4), 739-751.e735.

Jackson-Jones, L. H., Duncan, S. M., Magalhaes, M. S., Campbell, S. M., Maizels, R. M., McSorley, H. J., Allen, J. E., & Bénézech, C. (2016). Fat-associated lymphoid clusters control local IgM secretion during pleural infection and lung inflammation. Nature Communications, 7(1), 12651.

McSorley, H. J., Blair, N. F., Smith, K. A., Mckenzie, A. N. J., & Maizels, R. M. (2014). Blockade of IL-33 release and suppression of type 2 innate lymphoid cell responses by helminth secreted products in airway allergy. Mucosal Immunology, 7(5), 1068-1078.

Ferreira, I., Smyth, D., Gaze, S., Aziz, A., Giacomin, P., Ruyssers, N., Artis, D., Laha, T., Navarro, S., Loukas, A., McSorley, H. J., & Urban, J. F. (2013). Hookworm Excretory/Secretory Products Induce Interleukin-4 (IL-4)+ IL-10+ CD4+ T Cell Responses and Suppress Pathology in a Mouse Model of Colitis. Infection and Immunity, 81(6), 2104-2111.

McSorley, H. J., O'Gorman, M. T., Blair, N., Sutherland, T. E., Filbey, K. J., & Maizels, R. M. (2012). Suppression of type 2 immunity and allergic airway inflammation by secreted products of the helminth Heligmosomoides polygyrus. European Journal of Immunology, 42(10), 2667-2682.

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